Protein oxidation also affects surface proteins involved in sperm-egg recognition, further diminishing fertilization potential
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The catch is that a compounded drug product qualifies for these exemptions only if the bulk drug substance used to make it meets one of three criteria: (1) it complies with a USP or National Formulary monograph
However, further research studies reported that glutathione supplements taken for this purpose lead to problems that may include allergic reactions with itchy and irritated skin, fatigue, and erythema-producing redness spots on the skin
Madfes notes that kojic acid may be more effective in topical preparationssuch as serums and face creamsthan in soaps, which have limited contact with the skin and decreased efficacy, she explains